Preprint · bioRxiv · 2025-09-04
“Thermostable enzyme cascades enable selective single-vessel conversion of high-titre feedstocks”
Delta Lab, Example Institute of Technology · 4 authors · 87 citations
How could you trackall of this?
Every record below is landing right now, across 61 jurisdictions. This is a single minute of the field Lapis watches continuously.
Most of the frontiergoes unseen.
Patents, papers, grants, clinical developments, regulatory activity, and competitor programs move before the market notices. Lapis watches the field continuously and isolates what can change your roadmap.
1.6B+
records
61
jurisdictions
24 / 7
active
Scroll to open the perimeter
Founders Hub
Research Partner
Toronto Network
Schulich Startups
Featured · 2025
Podcast guestAutologyPartner
Research lab
Research Partner01 / The gap
You’re making multi-million dollar decisions on a fraction of the available science.
Most teams find out too late. That’s not bad luck. It’s a volume problem.
Patents publish 18 months after filing. The science behind them was happening years before that. 6,000 papers a day, 72,000 patents a week. No team on earth is reading even one percent of it.
New papers published since you opened this page
0.00
Volume vs. attention
Year
Papers / yr
M
Beyond capacity
×
Sources: NSF Science & Engineering Indicators · Scopus1996 → 2024 recorded · 2025 → 2035 projected
02 / What the gap cost
Fourteen months of public record. Six of them were a warning.
● Found in due diligence
Every one was public the day it appeared
Every one was public the day it appeared
14 mo
7 mo
Today
Public record · 14 months
03 / How it works
From public record to decision.
● Live
Click the three steps
Four streams, one evidence layer
Click the three steps
Four streams, one evidence layer
01 / Intake
Everything public arrives as evidence.
Four streams enter one layer: patents, papers, awards, and news. No source is read in isolation, because no single source is conclusive on its own.
04 / How a finding is made
Three records overnight. One finding by morning.
One record is noise. Three that converge are a finding. Three public records arrive between one and four in the morning, hours apart and meaningless on their own. Watch them link: the first two fall short of the threshold, the third carries it, and by 05:52 there is a finding with an organisation behind it and a next step attached.
Overnight · three public records
- 01:14 · PATENTUS 18/604,215Continuation crosses the defined continuous-process perimeter.PUBLIC+0.26
- 02:38 · PREPRINT10.1101/2026.03.04A related laboratory publishes the missing delivery evidence.PUBLIC+0.24
- 04:07 · GRANTR01 GM-215904Funding confirms sustained program intent.PUBLIC+0.22
Below threshold
Nothing has happened yet.
It is 01:00 and the record is quiet. Everything that arrives tonight is public, and none of it is addressed to you.
FINDINGPENDING
PROGRAM IMPACTWATCHING
URGENCYPENDING
Grant · NIH R01 · awarded 2025-06
GM-215904 · $1.8M over 4 years · same lead investigator
Mechanism: continuous enzymatic biomanufacturing for biologics
Patent · USPTO continuation · published 2026-01
Application 18/604,215, claims 3–7 overlap EBX-7 chemistry
Two prior-art references appear missing from prosecution
3 sources cited · full reasoning in app · fictional example, reasoning path preservedOpen full brief
05 / The product
Eight screens. All of them running 24/7.
This is the product a team opens on a Monday morning, in the order they use it.
What you open
The overnight read, waiting for you.
Six scouts read four thousand records overnight and sixty-four survived. The week's brief sits at the top with its bottom line, the findings run below it, and the public record keeps arriving down the right-hand side while you read.
06 / Intelligence terrain
The whole landscape, on one canvas.
Elevation reflects live research and filing density.
Booting console…
Elevation = filing density
Low groundHot peak
Domain summitWhite space (basin)
07 / What it watches
Global science, watched continuously.
Patent offices, regulators, institutions, filings, and collaborations connect across the jurisdictions and organizations moving your field. Grab the globe and spin it.
Jurisdictions and regulators are live
Loading country boundaries · drag to rotate · select a node
Every office the globe above is watching, pulled out and counted: 61 jurisdictions across the indexed patent corpus.
0.0B+
Records indexed
Patents, papers, grants, and the entities behind them
0
Jurisdictions covered
Patent authorities present in the corpus
0.00M
Hot tier, full text
Resolved, deduplicated, and searchable right now
08 / What it’s worth
See earlier. Defend the moat. Move with proof.
Lapis gives an early-stage leadership team the situational awareness of a dedicated intelligence function without adding another database, inbox, or analyst workflow.
01 / Strategic effect
See the incoming block
Identify the organization, technical direction, and overlap while there is still time to respond.
THREAT / EARLYEvidence linked
02 / Strategic effect
Defend the scientific moat
Know where claims are crowding, assumptions are shifting, and your position remains differentiated.
MOAT / MAPPEDEvidence linked
03 / Strategic effect
Act with evidence
Bring impact, urgency, confidence, original sources, and a practical response into one decision surface.
ACTION / READYEvidence linked
09 / How it behaves
Four rules it does not break.
01traceable
Every claim keeps its receipts.
No finding exists without the records underneath it. You can open the filing, the paper, and the award that produced the conclusion, and disagree with it if you want to.
02relative
Relevance is defined by your work.
The same patent is material to one program and noise to another. Lumen scores against your technology and roadmap, not against a keyword list that any competitor could guess.
03continuous
A search is a snapshot. This is not.
A freedom-to-operate search starts ageing the day it is delivered. A watched perimeter does not, because the landscape is re-read continuously and you are told what moved.
04auditable
You can see why it was surfaced.
Every finding carries the trail that produced it: when the record was ingested, what it was screened against, what it was cross-referenced to, and the moment it was escalated. Nothing arrives as a verdict you have to take on trust.
─── Why not just use ChatGPT
ChatGPT is great if you know what to ask. The hard part is knowing what you don’t know.
Once you know about a specific patent, anyone can summarize it. Finding it in the first place, across millions of documents, in 18-month-old data, before it shows up anywhere obvious, is the job Lapis does.
LapisA chatbotAnswers questions you already know to ask
LapisSurfaces the patent, lab, or grant you didn't know existed
A chatbotReads what you paste in
LapisReads every filing and preprint in your field, end to end
A chatbotStops when you close the tab
LapisRuns every day, on a schedule, while you're doing your job
A chatbotGeneric answers, hallucinated citations
LapisCited findings from primary sources, with reasoning